Molecular Diagnostics Laboratory

Laboratory Overview

The Molecular Diagnostics Laboratory is operated as a reference laboratory by the Department of Pathology at UT Health San Antonio. The laboratory is involved in teaching medical students, residents, and fellows, and also provides support services for faculty and staff of UT Health, as well as services to outside entities on a fee-for-service basis.

The laboratory develops and performs molecular diagnostic tests for nucleic acid targets found in a variety of settings in medicine. The primary focus of the laboratory is hematopathology; a selection of genetic and infectious disease tests are also performed.

The Molecular Diagnostics Laboratory is fully accredited by and participates in the College of American Pathologists (CAP) inspection and accreditation programs. Through the deemed status granted to the CAP, the laboratory is also accredited by the Health Care Financing Administration through the Clinical Laboratory Improvement Act (CLIA) for the performance of high complexity testing. Current certificates of accreditation may be viewed here: CAP, CLIA.*

Test Menu

Tests Currently Performed by the Molecular Diagnostics Laboratory

Hematopathology

BCR-ABL p210 quantitation by real-time PCR and report on IS

BCR-ABL p190 quantitation by real-time PCR

PML-RARα Translocation t(15;17) by Real-time PCR

BCL2 translocation major breakpoint by real-time PCR

JAK2 mutation (V617F) detection by real-time PCR

IGH clonality detection by PCR and capillary electrophoresis

IG kappa Gene Clonality Detection by PCR and Capillary Electrophoresis

TCR gamma clonality detection by PCR and capillary electrophoresis

TCR beta clonality detection by PCR and capillary electrophoresis

 

Inherited disease

F5 Leiden (R506Q) mutation by Real-Time PCR

Prothrombin (F2) G20210A mutation by Real-Time PCR

Hemochromatosis (HFE) 2 Mutations

 

Infectious disease

Molecular identification of fungi (order through the Fungal Testing Laboratory)

Meet our staff>>