ROBERT L. REDDICK, M.D.
Chair and the Frank M. Townsend, M. D. Professor of Pathology

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Department of Pathology – Mail Code 7750
The University of Texas Health Science Center
7703 Floyd Curl Drive
San Antonio, Texas 78229-3900
INFORMATION
Email: reddick@uthscsa.edu
Phone: (210) 567-4001   Fax: (210) 567-6729


EDUCATION
1969 BA, Chemistry.  University of North Carolina at Chapel Hill
1971 MS, Exptl Pathology. University of North Carolina at Chapel Hill
1973 MD. University of North Carolina at Chapel Hill
 
TRAINING
1973-74 Intern and postdoctoral trainee, Department of Pathology UNCCH
1974-75 Resident and postdoctoral trainee, Department of Pathology UNCCH
1975-76 Resident, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD
1977-78 Senior Investigator, National Cancer Institute, National Institutes of Health, Bethesda, MD
 
HONORS AND AWARDS
1970 MacNider Award, University of North Carolina, School of Medicine
1970-71 Martin L. King, Jr., Fellowship
1973 Sheard-Sanford Award
1983-86 American Cancer Society Junior Faculty Development Award
1986 Student National Medical Association Service Award
1989-96 First Kenneth M. Brinkhous Distinguished Professor, Department of Pathology, University of North Carolina, School of Medicine
1997 16th Brindley Visiting Professor of Pathology, University of Texas Medical Branch, Galveston, Texas


PROFESSIONAL SOCIETY MEMBERSHIPS
1. United States and Canadian Academy of Pathology
2. American Society of Investigative Pathology
3. Texas Society of Pathologists


RESEARCH ACTIVITIES/CLINICAL EXPERTISE
1. Anatomic Pathology, Certified by the American Board of Pathology
    a. General Surgical Pathology (breast, lung, soft tissue)
    b. Autopsy Pathology
    c. Electron Microscopy

2. Genetic synthesis of atherosclerosis
    a. Investigations to determine the atherogenic phenotype of newly created mouse models
    b. Investigations using mutant mouse models to identify specific and combinations of factors that influence atherogenesis

3. Genetic and epigenetic studies of aging
    a. Evaluation of the pathologic changes associated with aging in normal mice
    b. Evaluation of the histopathologic changes that occur with aging in calorically restricted mice
    c. Histopathologic changes associated with mutation accumulation in mice of extended life span


SELECTED PUBLICATIONS
1. Zhang SH, Reddick RL, Piedrahita JA, Maeda N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992;258:468-471

2. Reddick RL, Read MS, Brinkhous KM, Bellinger DA, Nichols TC, Griggs TR. Coronary atherosclerosis in the pig. Induced plaque injury and platelet response. Arteriosclerosis 1990;10:541-550

3. Reddick RL, Zhang SM, Maeda N. Atherosclerosis in mice lacking apolipoprotein E. Evaluation of lesional development and progression. Arterioscler Thromb 1994;14:141-147

4. Reddick RL, Zhang SH, Maeda N. Aortic atherosclerotic plaque injury in apolipoprotein E deficient mice. Atherosclerosis 1998;140:297-305

5. Maeda N, Hagihara H, Nakata Y, Hiller S, Wilder J, Reddick R. Aortic wall damage in mice unable to synthesize ascorbic acid. Proc Natl Acad Sci USA 2000;97:841-846

6. Hodgin J, Krege J, Reddick R, Korach K, Smithies O, Maeda N. Estrogen receptor {alpha} is a major mediator of 17ß-estradiol’s atheroprotective effect on lesion size in Apoe-/- mice. J Clin Invest 2001;107:333-340

7. Zhou Z-Q, Manguino D, Kewitt K, Intano GW, McMahan CA, Herbert DC, Hanes M, Reddick R, Ikeno Y, Walter CA. Spontaneous hepatocellular carcinoma is reduced in transgenic mice overexpressing human O6-methylguanine-DNA methyltransferase. Proc Natl Acad Sci USA 2001;98:12566-12571

8. Jiao-Hui W, Hagaman J, Kim S, Reddick RL, Maeda N. Aortic constriction exacerbates atherosclerosis and induces cardiac dysfunction in mice lacking apolipoprotein E. Arterioscler Thromb Vasc Biol 2002;22:469-475

Updated on 04/17/2002